Harmonised approach for the risk assessment of compounds which are both genotoxic and carcinogenic

Opinion of the Scientific Committee on a request from EFSA related to A Harmonised Approach for Risk Assessment of Substances Which are both Genotoxic and Carcinogenic (Request No EFSA-Q-2004-020)

Approaches to the risk assessment of genotoxic carcinogens in food: a critical appraisal.

The present paper examines the particular difficulties presented by low levels of food-borne DNA-reactive genotoxic carcinogens, some of which may be difficult to eliminate completely from the diet, and proposes a structured approach for the evaluation of such compounds. While the ALARA approach is widely applicable to all substances in food that are both carcinogenic and genotoxic, it does not...

Health risk assessment of heavy metals, BTEX and polycyclic aromatic hydrocarbons (PAHs) in the workplace in a secondary oil re-refining factory

The present study aimed to evaluate the health risk of heavy metals (iron, zinc, cadmium, arsenic, nickel, lead, and mercury), benzene, toluene, ethylbenzene and xylene (BTEX), and polycyclic aromatic hydrocarbons (PAHs) in the workplace in a secondary oil re-refining factory. In this descriptive, cross-sectional study, samples were collected and analyzed using the NIOSH 1501 method at eight sa...

Assessment of Sources and Health Risks of Polycyclic Aromatic Hydrocarbons (PAHs) in the Street Dust of Dezful City

Street dust is mainly affected by the pollution of polycyclic aromatic hydrocarbons (PAHs). PAHs are a group of organic pollutants consisting of two or more benzene rings and are mainly produced during incomplete combustion. PAHs have attracted widespread attention due to their high carcinogenic and mutagenic properties in humans. Therefore, the purpose of this study was to investigate the sour...

Risk ranking priority of carcinogenic and/or genotoxic environmental contaminants in food in Belgium.

This paper focuses on the risks of environmental carcinogenic and/or genotoxic contaminants in food. It describes, for each contaminant studied, the carcinogenicity and genotoxicity, the toxicological reference values, the exposure and the risk characterisation. The compounds studied were classified into 3 categories based on a risk assessment. Effects others than carcinogenicity and/or genotox...